抽象的な
Primary cardiac CD5-positive diffuse large B-cell lymphoma with bcl-6 gene rearrangement: A case report and review of literature
Hanjin Yang, Qiqi Gao, Xu Yang, Zhaoming WangBackground: Primary cardiac CD5 positive Diffuse Large B-Cell Lymphoma (CD5+ DLBCL) with bcl-6 gene rearrangement is a rare subtype of DLBCL. The case is reported, along with a review of several characteristics of the disease.
Case presentation: We described a 64-year-old female patient who presented with a 12-month history of cough. Magnetic Resonance Imaging (MRI) revealed the mass in the right atrium and extending into the right ventricle.
Conclusion: CD5+ DLBCL was confirmed finally by pathological examination of the cardiac biopsy. The patient responded well to the modified R-CHOP regime. In a review of primary literatures, we know that factors contributing to the poor prognosis of DLBCL including CD5 positive, non-GCB immunophenotype, myc, bcl-2 and bcl- 6 gene rearrangements etc. Early diagnosis and aggressive treatment play a key role on improving the prognosis of primary cardiac CD5+ DLBCL.