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Autoimmune sensory ganglionopathy in primary Sjögren’s syndrome treated with combination therapy of cyclophosphamide and rituximab: a case-based review

Aadil Al Ghafri, Christopher McGuigan & Eamonn Molloy

A 45 year-old male with initial presentation with central nervous system involvement and sensory ganglionopathy, with ultimate diagnosis of primary Sjögren’s syndrome (PSS). Progressive disease was noted despite initial treatment with high-dose steroids and intravenous immunoglobulins (IVIg). He subsequently had an excellent response to combination therapy of intravenous cyclophosphamide (CYC) and rituximab (RTX).